Journal of Translational Critical Care Medicine

CONSENSUS
Year
: 2019  |  Volume : 1  |  Issue : 2  |  Page : 52--56

Pragmatic Studies for Acute Kidney Injury: Fluid Resuscitation in the Peri-Acute Kidney Injury Period


Raghavan Murugan1, Haibo Qiu2, Thomas Rimmele3, Jianguo Li4, Zhiyong Peng4, Kaijiang Yu5, John A Kellum1, Claudio Ronco6 
1 Department of Critical Care Medicine, Center for Critical Care Nephrology, CRISMA, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
2 Department of Critical Care Medicine, School of Medicine, Zhongda Hospital, Southeast University, Nanjing, China
3 Department of Anesthesiology and Critical Care Medicine, Edouard Herriot Hospital, Lyon, France
4 Department of Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China
5 Department of Critical Care Medicine, The Third Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China
6 Department of Nephrology, Dialysis and Transplantation, International Renal Research Institute of Vicenza, San Bortolo Hospital, Vicenza, Italy

Correspondence Address:
Prof. Raghavan Murugan
Department of Critical Care Medicine, Center for Critical Care Nephrology, CRISMA, University of Pittsburgh School of Medicine, 3347 Forbes Avenue, Suite 220, Rm 206, Pittsburgh, Pennsylvania 15213
USA

How fluid resuscitation clinical trials should be conducted for either prevention or treatment of acute kidney injury among patients admitted to the intensive care unit is unclear. In 2017, a group of experts in fluid resuscitation and acute kidney injury met at the Acute Disease Quality Initiative (ADQI) XIX consensus conference on “Pragmatic Studies for AKI”, Wuhan, China and developed a research framework. In this report, we summarize the consensus recommendations on the topic of fluid resuscitation in the peri-AKI period based on existing clinical evidence. We also discuss the gaps in our knowledge and identify future research questions. Finally, we examine the feasibility of conducting a pragmatic fluid resuscitation trial to improve outcomes from acute kidney injury.


How to cite this article:
Murugan R, Qiu H, Rimmele T, Li J, Peng Z, Yu K, Kellum JA, Ronco C. Pragmatic Studies for Acute Kidney Injury: Fluid Resuscitation in the Peri-Acute Kidney Injury Period.J Transl Crit Care Med 2019;1:52-56


How to cite this URL:
Murugan R, Qiu H, Rimmele T, Li J, Peng Z, Yu K, Kellum JA, Ronco C. Pragmatic Studies for Acute Kidney Injury: Fluid Resuscitation in the Peri-Acute Kidney Injury Period. J Transl Crit Care Med [serial online] 2019 [cited 2021 Jun 24 ];1:52-56
Available from: http://www.tccmjournal.com/article.asp?issn=2665-9190;year=2019;volume=1;issue=2;spage=52;epage=56;aulast=Murugan;type=0